doi: 10.1016/0016-5085(79)90002-7
Our study is not free from limitations, which can be addressed in future studies
Prior to injections, the ocular surface was sterilized with povidone-iodine, and 0.5% proparacaine hydrochloride anesthetic eye drops were applied
Additionally, mRNA expression of iron response element binding protein 2, encodes a master regulator of iron metabolism), and CS (citrate synthase, regulating the mitochondrial fatty acid metabolism) was upregulated in both models, while ACSF2 ((acyl-CoA synthetase family member 2, regulating the mitochondrial fatty acid metabolism) was upregulated only in APPswe/PS1dE9 mice
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Body weight was measured using a digital scale (Tanita HD-319 scale, Sin Huat Hin Machinery (M) Sdn.Bhd., Serdang, Kuala Lumpur, Malaysia), to the nearest 0.1 kg